Obat Anti Malaria

Potent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

Potent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

Malaria and Anti-ddt Campaigns

Donald R. Roberts, Ph.D. Professor Emeritus, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA describes the successful history of the use of DDT for the eradication of malaria and how single issue anti-DDT campaigners have compromised the success of this programme. Email:[email protected] Contact information:118 First St, Clifton Forge, VA 2...

Anti-malaria drug blocks proteotoxic stress response: anti-cancer implications.

The number of physical conditions and chemical agents induce accumulation of misfolded proteins creating proteotoxic stress. This leads to activation of adaptive pro-survival pathway, known as heat shock response (HSR), resulting in expression of additional chaperones. Several cancer treatment approaches, such as proteasome inhibitor Bortezomib and hsp90 inhibitor geldanamycin, involve activati...

Malaria Control by Anti-Mosquito Measures